Professor and Chair, Division of Biomedical Sciences

Associate Dean, UCR/UCLA Thomas Haider Program in Biomedical Sciences

Ph.D., University of Massachusetts, Amherst

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The study of the interaction of bacterial pathogens with human host defenses; analysis of the microbial physiology, genetics, immunobiology and pathogenesis of Pseudomonas aeruginosa infection in cystic fibrosis patients; characterization of antibiotic resistance in Helicobacter pylori.

Albrecht, M.T. and Schiller, N.L.  2005.  Alginate lyase (AlgL) activity is required for alginate biosynthesis in Pseudomonas aeruginosa.  J. Bacteriol. (in press).

Robles-Price, A., Wong, T.A., Sletta, H., Valla, S. and Schiller, N.L.  2004.  AlgX is a periplasmic protein required for alginate biosynthesis in Pseudomonas aeruginosa.  J. Bacteriol. 186: 7369-7377.

Albrecht, M.T., Wang, W., Shamova, O., Lehrer, R.I. and Schiller, N.L. 2002. Binding of protegrin-1 to Pseudomonas aeruginosa and Burkholderia cepacia -- art. no. 18. Resp. Res. 3: U1-U11.

Preston, L.A., C.L. Bender and N.L. Schiller. 2001. Analysis and expression of algL, which encodes alginate lyase in Pseudomonas syringae pv. syringae. DNA Sequence 12: 455-461.

Preston, L., T.-Y. Wong, C. Bender and N.L. Schiller. 2000. Characterization of alginate lyase from Pseudomonas syringae pv. syringae. J. Bacteriol. 182: 6268-6271.

DeLoney, C.R. and N.L. Schiller. 2000. Characterization of an in vitro-selected amoxicillin-resistant strain of Helicobacter pylori. Antimicrob. Agents Chemother. 44: 3368-3373.

Wong, T.Y., L.A. Preston and N.L. Schiller. 2000. Alginate Lyase: review of major sources and enzyme characteristics, structure-function analysis, biological roles, and applications. Ann. Rev. Microbiol. 54: 289-340.

DeLoney, C.R. and N.L. Schiller. 1999. Competition of various b-lactam antibiotics for the major penicillin-binding proteins of Helicobacter pylori: Antibacterial activity and effects on bacterial morphology. Antimicrob. Agents Chemother. 43: 2702-2709.

Lehmann, F., N. Schiller, T. Cover, R. Hatch, R. Seensalu, K. Kato, J. Walsh and A. Soll. 1998. Helicobacter pylori stimulates gastrin release from canine antral cells in primary culture. Am. J. Physiol. 274 (Gastrointest. Liver Physiol. 37): G993-G996.

Hatch, R.A. and N.L. Schiller. 1998. Alginate lyase promotes the diffusion of aminoglycosides through the extracellular polysaccharide of mucoid Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 42: 974-977.

McClure, C. D. and N. L. Schiller. 1996. Inhibition of macrophage phagocytosis by Pseudomonas aeruginosa rhamnolipids in vitro and in vivo. Current Microbiol. 33: 109-117.

Monday, S. R. and N. L. Schiller. 1996. Alginate synthesis in Pseudomonas aeruginosa: the role of ALgL (alginate lyase) and AlgX. J. Bacteriol. 178: 625-632.

Eftekhar, F. and N. L. Schiller. 1994 Partial purification and characterization of a mannuronan-specific alginate lyase from Pseudomonas aeruginosa. Current Microbiol. 29: 37-42.

Schiller N. L., S. R. Monday, C. M. Boyd, N. T. Keen and D. E. Ohman. 1993. Characterization of Pseudomonas aeruginosa alginate lyase gene (algL): Cloning, sequencing and expression in Escherichia coli. J. Bacteriol. 175: 4780-4789.